Eva Zimmermann, Udo Seifert
In a single molecule assay, the motion of a molecular motor is often inferred from measuring the stochastic trajectory of a large probe particle attached to it. We discuss a simple model for this generic set-up taking into account explicitly the elastic coupling between probe and motor. The combined dynamics consists of discrete steps of the motor and continuous Brownian motion of the probe. Motivated by recent experiments on the F1-ATPase, we investigate three types of efficiencies both in simulations and a Gaussian approximation. Overall, we obtain good quantitative agreement with the experimental data. In particular, we clarify the conditions under which one of these efficiencies becomes larger than one.
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http://arxiv.org/abs/1209.3667
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